Due to the large number of educated in the adrenal gland hormones can occur in a variety of adrenal gland disorders and diseases.
Through a disease of the organ due to overproduction of aldosterone called aldosteronism (Conn’s syndrome) with increased blood pressure and low potassium blood levels. The cause of the hyperaldosteronism is either unilateral adrenal tumors (Conn’s adenoma) or a bilateral enlargement of the adrenal gland (bilateral hyperplasia). Besides the “classic” cases of Conn’s syndrome “normokalemic” (potassium levels within the normal range), Conn’s syndrome much more often and to review the most common causes of endocrine-related hypertension. A sub-function of the adrenal cortex is called hypoaldosteronism. It occurs mainly in primary adrenal insufficiency (Addison’s disease) and the adrenogenital syndrome.
Increased glucocorticoid leads to the formation hyperadrenocorticism (Cushing’s disease). This is more common in humans but also in dogs and horses (equine Cushing’s syndrome). Mainly caused the overproduction of adrenocorticotropic hormone (ACTH) in the pituitary gland, which regulates the formation of corticosteroids in the adrenal gland, rare disease of the adrenal cortex itself, the resultant Cushing syndrome manifested in increased blood sugar levels, truncal obesity, skin changes and bone – and muscle breakdown. Long-time applications with anti-inflammatory glucocorticosteroids (such as prednisolone or dexamethasone) have corresponding side effects. Decreased glucocorticoid formation known as Hypadrenokortiz ism, often combined with a general adrenal insufficiency (Addison’s disease). This is demonstrated by rapid fatigue, loss of appetite, weight loss and advanced through a dark, brown-yellow skin color. Sub-functions of the adrenal gland are very rare. By tumors (pheochromocytoma, ganglioneuroma) is a conditional function in seizure type hypertension (paroxysmal hypertension) comment. An acute failure of the adrenal function (Waterhouse-Friderichsen syndrome) may occur in septicemia.
The Myelolipom is a benign tumor that is associated mostly without clinical symptoms.